Definium Therapeutics is a late-stage clinical biopharmaceutical company and our mission is to forge a new era of psychiatry by applying scientific rigor to psychedelics, with the goal of developing accessible treatments that unlock healing at scale.

Our lead product candidate, lysergide tartrate (our proprietary orally disintegrating tablet form of lysergide (LSD) D-tartrate), represents a highly differentiated, potential best-in-class opportunity for patients suffering from generalized anxiety, major depressive disorder, and posttraumatic stress disorder. Our early stage pipeline includes DT402, the R-enantiomer of MDMA and is under development to target the core symptoms of autism spectrum disorder (ASD), specifically addressing social communication challenges.

Guided by the recognition that patients deserve more than better, Definium is relentlessly advancing a new generation of therapeutics intended to address the underlying causes of psychiatric and neurological disorders. By turning evidence into impact, Definium aims to change the trajectory of today’s mental health care crisis and enable a healthier future. Headquartered in New York, Definium Therapeutics trades on Nasdaq under the symbol DFTX.

Together we are moving psychiatry forward—beyond better, into a boundless future. Join us!

The Senior Manager, Medical Marketing will support the development and execution of strategic medical marketing initiatives to drive the successful commercial launch of DT120, working closely with Medical Affairs, Regulatory, Commercial, Clinical Development, and cross-functional teams to align with corporate goals. This role will help shape scientific engagement strategy through KOL development, advisory boards, congress activities, and evidence communication initiatives, while ensuring all activities meet applicable regulatory and compliance standards.

Responsibilities

Develop and execute medical marketing initiatives that support the scientific positioning and successful commercialization of DT120
Lead KOL engagement strategy, including identification, segmentation, relationship development, and ongoing engagement planning
Manage advisory board planning and execution, including objectives, attendee selection, content development, logistics, and insight capture
Support medical congress strategy and execution, including sponsorships, exhibits, symposia, scientific communications, and stakeholder engagement activities
Partner with Medical Affairs, Clinical Development, Commercial, and Regulatory teams to align scientific engagement activities with broader organizational objectives
Direct external agency partners and vendors supporting congresses, advisory boards, speaker programs, and scientific communications initiatives
Gather and synthesize insights from KOL interactions, advisory boards, congresses, and market intelligence to inform brand and evidence-generation strategies
Support development of scientific communication materials and engagement initiatives that strengthen awareness, credibility, and launch readiness

Qualifications

Bachelor's degree in Life Sciences, Marketing, Business, Communications, or related discipline; advanced degree preferred
Minimum 8 years in the pharmaceutical, biotech, or healthcare industry, with experience in medical marketing, medical affairs operations, scientific communications, or commercial launch support
Strong understanding of pharmaceutical regulations governing scientific exchange, promotional activities, and healthcare professional engagement
Experience managing KOL engagement programs, advisory boards, and medical congress activities required
Proven ability to lead initiatives and influence cross-functional teams in a matrixed environment
Proficiency in analyzing scientific, clinical, and market insights to inform strategic decision-making
Skilled in cross-functional collaboration; intellectually curious, solutions-oriented, and effective at communicating and socializing strategic recommendations
Launch experience in the U.S. pharmaceutical market preferred
Experience supporting scientific communications, congress planning, speaker programs, or publication-related activities preferred
Experience in CNS / psychiatry, specialty pharmaceutical, or complex treatment categories preferred
Experience with REMS products or novel treatment delivery models preferred
Ability to synthesize complex clinical and market data into actionable strategies
Strong presentation skills and ability to influence senior, cross-functional, KOL, and agency stakeholders
Ability to travel as required; average 20–30%, with higher travel during congress and launch periods

The starting base pay range for this position is $170,000.00-197,911.00, with compensation determined based on several factors including skill set, years of experience, and geographic location.

Employees in this role may be entitled to additional compensation, including bonus and equity. Benefits information is listed on our Jobs Page. The Company provides competitive benefits to employees including:

100% paid health benefits including Medical, Dental and Vision for you and your dependents
401(k) program with company match and vesting after the turn of the first month after your start date
Flexible time off
Generous parental leave and some fun fringe perks!

Definium Therapeutics

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Senior Manager, Medical Marketing